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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
|
pubmed:dateCreated |
1992-3-17
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pubmed:abstractText |
The expression of major histocompatibility complex (MHC) class II (HLA-DR) antigens on M cells within follicle-associated epithelial cells (FAE) covering Peyer's patches was analyzed immunohistochemically. HLA-DR antigens were strongly expressed on M cells and cells with dendritic morphology, whereas other FAE covering Peyer's patches showed weak, but definite staining. Dendritic cells were also positive for S-100 protein and IL-1. These findings suggest that M cells as well as dendritic cells within FAE form an antigen-presenting cell system and contribute to the first information releaser for the mucosal immune system.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
|
pubmed:issn |
0001-6632
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
818-23
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1785342-Dendritic Cells,
pubmed-meshheading:1785342-Epithelial Cells,
pubmed-meshheading:1785342-Epithelium,
pubmed-meshheading:1785342-HLA-DR Antigens,
pubmed-meshheading:1785342-Humans,
pubmed-meshheading:1785342-Immunohistochemistry,
pubmed-meshheading:1785342-Interleukin-1,
pubmed-meshheading:1785342-Intestinal Mucosa,
pubmed-meshheading:1785342-Intestine, Small,
pubmed-meshheading:1785342-Microscopy, Electron,
pubmed-meshheading:1785342-Peyer's Patches,
pubmed-meshheading:1785342-S100 Proteins
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pubmed:year |
1991
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pubmed:articleTitle |
HLA-DR expression on M cells overlying Peyer's patches is a common feature of human small intestine.
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pubmed:affiliation |
Department of Pathology, Tohoku University School of Medicine, Sendai, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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