Linked Life Data

1785256

Source:http://linkedlifedata.com/resource/pubmed/id/1785256

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1992-3-18
pubmed:abstractText
A primary axonal disease affecting the central and peripheral nervous system was discovered in a new mutant strain of the Japanese quail, named quiver (Quv). Quv showed significantly smaller cross-sectional areas of the cervical spinal cord and the optic and sciatic nerves, when compared with controls by light microscopic morphometry. In the cervical spinal cord, electron microscopic morphometry indicated that myelinated axons in Quv were significantly smaller in size than in controls, though greater in density. The axonal circularity was not significantly different from that of controls. Electron microscopically and immunohistochemically, neurofilaments were not detected in the axons or neuronal cell bodies. Axons in Quv were composed mainly of microtubules, which were increased in number in relation to the axonal size. From these findings, the lesions observed in Quv were regarded as axonal hypotrophy (growth arrest or retardation) due to altered neurofilament expression.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0001-6322
pubmed:author
pubmed:issnType
Print
pubmed:volume
82
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
427-34
pubmed:dateRevised
2007-11-9
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Hereditary hypotrophic axonopathy with neurofilament deficiency in a mutant strain of the Japanese quail.
pubmed:affiliation
Department of Comparative Pathology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
pubmed:publicationType
Journal Article