Linked Life Data

1785227

Source:http://linkedlifedata.com/resource/pubmed/id/1785227

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1992-3-19
pubmed:abstractText
Hematopoietic growth factors are the major regulatory molecules supporting constitutive and inducible hematopoiesis. Molecular biology techniques have led to the identification and cloning of a series of hematopoietic growth factor genes, and the synthesis of large amounts of these molecules has facilitated investigations or their physiological functions and the network of their interactions. The present article focuses on the role of hematopoietic growth factors, growth-factor-synergizing factors, and growth-factor-releasing factors in the regulation of proliferation, differentiation, and functional activation of hematopoietic stem cells and lineage-committed progenitor cells. Cellular sources of growth factors, signal transduction pathways involved in their gene activation and transcriptional and posttranscriptional mechanisms that govern regulation of expression of these genes are also detailed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-5792
pubmed:author
pubmed:issnType
Print
pubmed:volume
86
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
128-37
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Hematopoietic growth factors: interactions and regulation of production.
pubmed:affiliation
Department of Internal Medicine I (Hematology and Oncology), University of Freiburg Medical Center, FRG.
pubmed:publicationType
Journal Article, Review