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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2008-1-4
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pubmed:abstractText |
The etiology of periodontitis is related to the interaction between micro-organisms and host responses. Host modifying factors, such as genetic predisposition, may increase the severity of periodontitis. Recent works have shown that the levels of cytokine expression are regulated by genetic polymorphisms, and that these variations can interfere with progression of the disease. This study therefore aimed to evaluate whether interleukin (IL) 4 gene polymorphisms are associated with severe generalized chronic periodontitis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
D
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1502-3850
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
292-7
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17851828-Adolescent,
pubmed-meshheading:17851828-Adult,
pubmed-meshheading:17851828-Aged,
pubmed-meshheading:17851828-Case-Control Studies,
pubmed-meshheading:17851828-Chronic Disease,
pubmed-meshheading:17851828-Gene Frequency,
pubmed-meshheading:17851828-Humans,
pubmed-meshheading:17851828-Interleukin-4,
pubmed-meshheading:17851828-Introns,
pubmed-meshheading:17851828-Male,
pubmed-meshheading:17851828-Middle Aged,
pubmed-meshheading:17851828-Periodontitis,
pubmed-meshheading:17851828-Polymerase Chain Reaction,
pubmed-meshheading:17851828-Polymorphism, Single Nucleotide,
pubmed-meshheading:17851828-Promoter Regions, Genetic,
pubmed-meshheading:17851828-Repetitive Sequences, Nucleic Acid,
pubmed-meshheading:17851828-Turkey
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pubmed:year |
2007
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pubmed:articleTitle |
Association of the polymorphisms in promoter and intron regions of the interleukin-4 gene with chronic periodontitis in a Turkish population.
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pubmed:affiliation |
Department of Medical Biology and Genetics, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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