Mice disrupted for the interleukin (IL)-18 gene appear more disposed to preterm delivery (PTD) induced by inflammation. A synergy between IL-18 and IL-12 has been suggested. The objective of this study was to investigate a possible relation between human maternal serum levels of IL-18, IL-12 and spontaneous PTD.
North Atlantic Neuro-Epidemiology Alliances, Institute of Public Health, University of Aarhus, Vennelyst Boulevard 6, DK-8000 Aarhus, Denmark. ekelund@dadlnet.dk