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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-11-20
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pubmed:abstractText |
Diabetic retinopathy is a highly prevalent cause of visual loss in Western countries. Vascular endothelial growth factor (VEGF) is a potent angiogenic factor implicated in the development of the proliferative stage of this disease. Reports have suggested that polymorphisms at positions -460 and -634 of the 5' untranslated region of the VEGF gene increase its basal promoter activity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1435-702X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
246
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
39-43
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pubmed:meshHeading |
pubmed-meshheading:17849138-5' Untranslated Regions,
pubmed-meshheading:17849138-Aged,
pubmed-meshheading:17849138-Diabetes Mellitus, Type 2,
pubmed-meshheading:17849138-Diabetic Retinopathy,
pubmed-meshheading:17849138-Female,
pubmed-meshheading:17849138-Gene Frequency,
pubmed-meshheading:17849138-Genotype,
pubmed-meshheading:17849138-Humans,
pubmed-meshheading:17849138-Male,
pubmed-meshheading:17849138-Middle Aged,
pubmed-meshheading:17849138-Polymerase Chain Reaction,
pubmed-meshheading:17849138-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:17849138-Polymorphism, Single Nucleotide,
pubmed-meshheading:17849138-Promoter Regions, Genetic,
pubmed-meshheading:17849138-Vascular Endothelial Growth Factor A
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pubmed:year |
2008
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pubmed:articleTitle |
An association between vascular endothelial growth factor gene promoter polymorphisms and diabetic retinopathy.
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pubmed:affiliation |
Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland. jacek@amwaw.edu.pl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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