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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2008-2-18
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pubmed:abstractText |
Lifestyle and genetic factors interact in the development of obesity and the metabolic syndrome. The molecular mechanisms underlying the beneficial dietary modifications are, however, unclear. We aimed to examine the effect of the long-term moderate weight reduction on gene expression in adipose tissue (AT) and to identify genes and gene clusters responsive to treatment and thereby likely contributing to the development of the metabolic syndrome.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1476-5497
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pubmed:author |
pubmed-author:GyllingHH,
pubmed-author:KallioPP,
pubmed-author:KekäläinenJJ,
pubmed-author:KolehmainenMM,
pubmed-author:LaaksonenD EDE,
pubmed-author:LindiV IVI,
pubmed-author:MagerUU,
pubmed-author:NiskanenLL,
pubmed-author:PulkkinenLL,
pubmed-author:RauramaaRR,
pubmed-author:SalopuroTT,
pubmed-author:SchwabU SUS,
pubmed-author:SiitonenNN,
pubmed-author:SiveniusKK,
pubmed-author:UusitupaMM
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pubmed:issnType |
Electronic
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
292-303
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:17848939-Adult,
pubmed-meshheading:17848939-Aged,
pubmed-meshheading:17848939-Blood Glucose,
pubmed-meshheading:17848939-Case-Control Studies,
pubmed-meshheading:17848939-Cell Death,
pubmed-meshheading:17848939-Extracellular Matrix,
pubmed-meshheading:17848939-Female,
pubmed-meshheading:17848939-Gene Expression Regulation,
pubmed-meshheading:17848939-Glucose Tolerance Test,
pubmed-meshheading:17848939-Humans,
pubmed-meshheading:17848939-Insulin,
pubmed-meshheading:17848939-Male,
pubmed-meshheading:17848939-Metabolic Syndrome X,
pubmed-meshheading:17848939-Middle Aged,
pubmed-meshheading:17848939-Obesity,
pubmed-meshheading:17848939-Weight Loss
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pubmed:year |
2008
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pubmed:articleTitle |
Weight reduction modulates expression of genes involved in extracellular matrix and cell death: the GENOBIN study.
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pubmed:affiliation |
School of Public Health and Clinical Nutrition, Clinical Nutrition and Food and Health Research Center, University of Kuopio, Kuopio, Finland. marjukka.kolehmainen@uku.fi
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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