17848193

Source:http://linkedlifedata.com/resource/pubmed/id/17848193

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0006142, umls-concept:C0596244, umls-concept:C1336624, umls-concept:C1366557, umls-concept:C1518474, umls-concept:C1882417
pubmed:dateCreated	2007-11-20
pubmed:abstractText	Transforming growth factor beta 1 (TGFB1) forms a signaling complex with transforming growth factor beta receptors 1 and 2 and has been described as both a tumor suppressor and tumor promoter. Single nucleotide polymorphisms in TGFB1 and a microsatellite in TGFBR1 have been investigated for association with risk of breast cancer, with conflicting results.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/CA 09001-27, http://linkedlifedata.com/resource/pubmed/grant/CA49449, http://linkedlifedata.com/resource/pubmed/grant/CA65725, http://linkedlifedata.com/resource/pubmed/grant/CA87969
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/100967800
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Protein-Serine-Threonine Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Transforming Growth..., http://linkedlifedata.com/resource/pubmed/chemical/TGF-beta type I receptor, http://linkedlifedata.com/resource/pubmed/chemical/TGFB1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta1
pubmed:status	MEDLINE
pubmed:issn	1471-2407
pubmed:author	pubmed-author:CoxDavid GDG, pubmed-author:HankinsonSusan ESE, pubmed-author:HunterDavid JDJ, pubmed-author:PenneyKathrynK, pubmed-author:PooK PKP
pubmed:issnType	Electronic
pubmed:volume	7
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	175
pubmed:dateRevised	2009-11-18
pubmed:meshHeading	pubmed-meshheading:17848193-Adult, pubmed-meshheading:17848193-Breast Neoplasms, pubmed-meshheading:17848193-Female, pubmed-meshheading:17848193-Humans, pubmed-meshheading:17848193-Microsatellite Repeats, pubmed-meshheading:17848193-Middle Aged, pubmed-meshheading:17848193-Polymorphism, Single Nucleotide, pubmed-meshheading:17848193-Promoter Regions, Genetic, pubmed-meshheading:17848193-Protein-Serine-Threonine Kinases, pubmed-meshheading:17848193-Receptors, Transforming Growth Factor beta, pubmed-meshheading:17848193-Risk, pubmed-meshheading:17848193-Transforming Growth Factor beta1
pubmed:year	2007
pubmed:articleTitle	TGFB1 and TGFBR1 polymorphisms and breast cancer risk in the Nurses' Health Study.
pubmed:affiliation	Program in Molecular and Genetic Epidemiology, Epidemiology Department, Harvard School of Public Health, USA. dcox@hsph.harvard.edu
pubmed:publicationType	Journal Article, Research Support, N.I.H., Extramural