|
rdf:type |
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lifeskim:mentions |
umls-concept:C0003595,
umls-concept:C0011900,
umls-concept:C0019904,
umls-concept:C1514562,
umls-concept:C1516691,
umls-concept:C1861733,
umls-concept:C1880389,
umls-concept:C1883204,
umls-concept:C1883221,
umls-concept:C2674356,
umls-concept:C2750816
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|
pubmed:issue |
9
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|
pubmed:dateCreated |
2007-9-11
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|
pubmed:abstractText |
Memory declines more rapidly with age in apolipoprotein E (APOE) epsilon4 carriers than in APOE epsilon4 noncarriers, and APOE epsilon4 homozygotes' cognitive performances correlate with stressors. These changes could represent presymptomatic disease in some, despite their youth.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0003-9942
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1306-11
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17846270-Aged,
pubmed-meshheading:17846270-Aging,
pubmed-meshheading:17846270-Alleles,
pubmed-meshheading:17846270-Apolipoprotein E4,
pubmed-meshheading:17846270-Cognition,
pubmed-meshheading:17846270-Cognition Disorders,
pubmed-meshheading:17846270-Female,
pubmed-meshheading:17846270-Heterozygote,
pubmed-meshheading:17846270-Homozygote,
pubmed-meshheading:17846270-Humans,
pubmed-meshheading:17846270-Intelligence Tests,
pubmed-meshheading:17846270-Language Tests,
pubmed-meshheading:17846270-Male,
pubmed-meshheading:17846270-Mental Disorders,
pubmed-meshheading:17846270-Mental Recall,
pubmed-meshheading:17846270-Middle Aged,
pubmed-meshheading:17846270-Neuropsychological Tests,
pubmed-meshheading:17846270-Psychiatric Status Rating Scales,
pubmed-meshheading:17846270-Psychomotor Performance,
pubmed-meshheading:17846270-Risk,
pubmed-meshheading:17846270-Wechsler Scales
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pubmed:year |
2007
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pubmed:articleTitle |
Cognitive domain decline in healthy apolipoprotein E epsilon4 homozygotes before the diagnosis of mild cognitive impairment.
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pubmed:affiliation |
Department of Neurology, Mayo Clinic, 13400 E Shea Blvd, Scottsdale, AZ 85259, USA. caselli.richard@mayo.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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