Linked Life Data

17827882

Source:http://linkedlifedata.com/resource/pubmed/id/17827882

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2007-9-10
pubmed:abstractText
Zygotic gene activation (ZGA) is the first event of gene expression after fertilization. Following fertilization, ZGA occurs within a short time interval depending on the animal species. Until ZGA, maternal proteins and transcripts stored in oocytes control embryonic development, indicating the importance of maternal factors for development. Somatic cell cloning also proves the potential of oocyte to reprogram the differentiated cell nuclei to embryonic nuclei. Recent studies show that the epigenetic modifications of nuclei play important roles in controlling gene expression during ZGA. However, the mechanisms that control ZGA remain largely unknown. This review will cover the current understanding of ZGA. Specifically, it will focus on the maternal factors that control gene expression during early embryogenesis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0916-8818
pubmed:author
pubmed:issnType
Print
pubmed:volume
53
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
707-15
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Zygotic gene activation and maternal factors in mammals.
pubmed:affiliation
Laboratory of Reproductive Biology, Graduate School of Agriculture, Kyoto University, Kyoto, Japan. oog1nao@kais.kyoto-u.ac.jp
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't