Linked Life Data

17826182

Source:http://linkedlifedata.com/resource/pubmed/id/17826182

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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2007-10-15
pubmed:abstractText
Recent EEG-fMRI studies have suggested a novel method of data fusion which uses single trial (ST) estimates of event-related potentials in the fMRI analysis. This is potentially very powerful, but rests on the assumption that the ST variability observed in EEG is reflected in the fMRI signal. The current study investigated this assumption and compared two different data processing strategies for each modality. Five subjects underwent separate EEG and fMRI sessions with checkerboard stimuli at two contrasts. EEG data were preprocessed using wavelet denoising and independent component analysis (ICA), whilst the general linear model and ICA were used for fMRI. Amplitudes and latencies of the P1 and N2 components of the visual evoked potential (VEP) were calculated for each trial. For fMRI, the amplitudes and latencies of the ST haemodynamic responses (HR) were calculated. Within modality, the results for the two processing methods were significantly correlated in the majority of data sets. Across modality, the average amplitudes of the VEPs and HRs were also significantly correlated. Examination of ST variability demonstrated that the amplitudes of the mean VEPs and HRs are both influenced by the latency variability of the ST responses to a greater extent than the amplitude variability. For high contrast stimuli the latency variability in EEG and fMRI was significantly correlated, with a similar trend seen for the low contrast stimuli. The results confirm the validity of examining both the EEG and fMRI signals on an ST basis and suggest an underlying neuronal origin in both modalities.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1053-8119
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
280-92
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Single trial variability of EEG and fMRI responses to visual stimuli.
pubmed:affiliation
School of Psychology and Birmingham University Imaging Centre (BUIC), University of Birmingham, Edgbaston, Birmingham B15 2TT, UK. a.p.bagshaw@bham.ac.uk
pubmed:publicationType
Journal Article