Source:http://linkedlifedata.com/resource/pubmed/id/17825944
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2007-10-8
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pubmed:abstractText |
Making multiple sequence alignments is one of the more commonplace procedures in modern biology. Multiple alignments are typically generated by feeding sequences into the alignment program from the N-terminus to the C-terminus. Recent results show that if the same sequences are processed from the C- to the N-terminus, a different alignment is often obtained. Because phylogenetic trees are built from alignments, the resulting trees can also differ. The new findings highlight sequence alignment as a crucial step in molecular evolutionary studies and provide straightforward measures to assess alignment reliability.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0168-9525
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
478-80
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pubmed:meshHeading |
pubmed-meshheading:17825944-Amino Acid Sequence,
pubmed-meshheading:17825944-Animals,
pubmed-meshheading:17825944-Evolution, Molecular,
pubmed-meshheading:17825944-Humans,
pubmed-meshheading:17825944-Molecular Sequence Data,
pubmed-meshheading:17825944-Phylogeny,
pubmed-meshheading:17825944-Sequence Alignment,
pubmed-meshheading:17825944-Sequence Analysis, Protein
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pubmed:year |
2007
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pubmed:articleTitle |
A reality check for alignments and trees.
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pubmed:affiliation |
Institute of Botany III, University of Düsseldorf, Düsseldorf, Germany. w.martin@uni-duesseldorf.de
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pubmed:publicationType |
Journal Article
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