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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
22
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pubmed:dateCreated |
2007-10-1
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pubmed:abstractText |
A series of pyrrolo[2,1-c][1,4]benzodiazepine-anthraquinone conjugates have been prepared and evaluated for their DNA binding ability as well as anticancer activity. Some of these molecules have shown significant anticancer activity in a number of cancer cell lines.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0968-0896
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6868-75
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pubmed:meshHeading |
pubmed-meshheading:17822905-Animals,
pubmed-meshheading:17822905-Anthraquinones,
pubmed-meshheading:17822905-Antineoplastic Agents,
pubmed-meshheading:17822905-Binding Sites,
pubmed-meshheading:17822905-Cattle,
pubmed-meshheading:17822905-Cell Line, Tumor,
pubmed-meshheading:17822905-Cell Proliferation,
pubmed-meshheading:17822905-DNA,
pubmed-meshheading:17822905-Drug Screening Assays, Antitumor,
pubmed-meshheading:17822905-Humans,
pubmed-meshheading:17822905-Molecular Structure,
pubmed-meshheading:17822905-Pyrroles,
pubmed-meshheading:17822905-Stereoisomerism,
pubmed-meshheading:17822905-Structure-Activity Relationship
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pubmed:year |
2007
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pubmed:articleTitle |
Synthesis, DNA binding, and cytotoxicity studies of pyrrolo[2,1-c][1,4]benzodiazepine-anthraquinone conjugates.
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pubmed:affiliation |
Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad 500 007, India. ahmedkamal@iict.res.in
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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