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rdf:type |
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lifeskim:mentions |
umls-concept:C0021745,
umls-concept:C0023981,
umls-concept:C0030685,
umls-concept:C0041290,
umls-concept:C0041296,
umls-concept:C0391871,
umls-concept:C0680255,
umls-concept:C0750491,
umls-concept:C1283071,
umls-concept:C1510438,
umls-concept:C1547564,
umls-concept:C1707455,
umls-concept:C1963578
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pubmed:issue |
7
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pubmed:dateCreated |
2007-9-6
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pubmed:abstractText |
Interferon-gamma release assays (IGRAs) are attractive alternatives to the tuberculin skin test (TST) for detecting Mycobacterium tuberculosis infection. However, the inability to definitively confirm the presence of most M. tuberculosis infections hampers assessment of IGRA accuracy. Although IGRAs are primarily indicated for the detection of latent tuberculosis infection, we sought to determine the sensitivity of the TST and 2 whole-blood IGRAs (QuantiFERON-TB assay [QFT] and QuantiFERON-TB Gold assay [QFT-G]) in situations in which infection is confirmed by recovery of M. tuberculosis by culture.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1537-6591
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
837-45
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17806047-Adolescent,
pubmed-meshheading:17806047-Adult,
pubmed-meshheading:17806047-Aged,
pubmed-meshheading:17806047-Aged, 80 and over,
pubmed-meshheading:17806047-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:17806047-False Negative Reactions,
pubmed-meshheading:17806047-Female,
pubmed-meshheading:17806047-Humans,
pubmed-meshheading:17806047-Interferon-gamma,
pubmed-meshheading:17806047-Male,
pubmed-meshheading:17806047-Middle Aged,
pubmed-meshheading:17806047-Mycobacterium tuberculosis,
pubmed-meshheading:17806047-Prospective Studies,
pubmed-meshheading:17806047-Reagent Kits, Diagnostic,
pubmed-meshheading:17806047-Sensitivity and Specificity,
pubmed-meshheading:17806047-Tuberculin Test,
pubmed-meshheading:17806047-Tuberculosis,
pubmed-meshheading:17806047-United States
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pubmed:year |
2007
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pubmed:articleTitle |
Prospective comparison of the tuberculin skin test and 2 whole-blood interferon-gamma release assays in persons with suspected tuberculosis.
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pubmed:affiliation |
Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. gym6@cdc.gov
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Multicenter Study,
Evaluation Studies
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