Linked Life Data

17804290

Source:http://linkedlifedata.com/resource/pubmed/id/17804290

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2007-11-26
pubmed:abstractText
Maltodextrin (MX) was fixed onto PVDF membranes in order to create a drug delivery Guided Tissue Regeneration (GTR) device with controlled drug delivery properties. PVDF microporous membranes were treated by a mixture of MX and citric acid, resulting to an 18 wt% increase of the supports. MX grafted membrane could capture 103 mg/g chlorhexidin digluconate (DigCHX) instead of 1mg/g for a virgin membrane. A neutralization step was performed before the biological tests. Viability tests confirmed the non-toxicity of the MX polymer coating after neutralisation. In vitro release test in human plasma, and microbiological tests showed that membranes grafted with MX were more performing compared to virgin and beta-CD grafted membranes. The antimicrobial activity was effective during more than 72 h.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1389-0344
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
472-6
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Functionalization of PVDF membranes with carbohydrate derivates for the controlled delivery of chlorhexidin.
pubmed:affiliation
Laboratoire de Chimie Organique et Macromoléculaire, Université des Sciences et Technologies de Lille, UMR CNRS 8009, 59655 Villeneuve d'Ascq Cedex, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't