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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2007-9-14
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pubmed:abstractText |
Mesothelin is a promising candidate for tumor-specific therapy because of its limited expression in normal tissues and high expression in several cancers. The expression of the protein mesothelin in hematological malignancies has not yet been analyzed. SS1(dsFv)PE38 is a recombinant anti-mesothelin immunotoxin which is undergoing clinical evaluation in patients with mesothelin-expressing tumors.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0902-4441
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
79
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
281-6
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pubmed:dateRevised |
2011-10-26
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pubmed:meshHeading |
pubmed-meshheading:17803679-Adolescent,
pubmed-meshheading:17803679-Antibodies, Monoclonal,
pubmed-meshheading:17803679-Blotting, Western,
pubmed-meshheading:17803679-Child,
pubmed-meshheading:17803679-Child, Preschool,
pubmed-meshheading:17803679-Drug Delivery Systems,
pubmed-meshheading:17803679-Drug Resistance, Neoplasm,
pubmed-meshheading:17803679-Drug Screening Assays, Antitumor,
pubmed-meshheading:17803679-Female,
pubmed-meshheading:17803679-GPI-Linked Proteins,
pubmed-meshheading:17803679-Gene Expression Regulation, Leukemic,
pubmed-meshheading:17803679-Humans,
pubmed-meshheading:17803679-Immunohistochemistry,
pubmed-meshheading:17803679-Immunotherapy,
pubmed-meshheading:17803679-Immunotoxins,
pubmed-meshheading:17803679-Infant,
pubmed-meshheading:17803679-Leukemia, Myeloid, Acute,
pubmed-meshheading:17803679-Male,
pubmed-meshheading:17803679-Membrane Glycoproteins,
pubmed-meshheading:17803679-Neoplasm Proteins,
pubmed-meshheading:17803679-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2007
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pubmed:articleTitle |
Mesothelin, a possible target for immunotherapy, is expressed in primary AML cells.
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pubmed:affiliation |
University Children's Hospital Jena, Germany. Daniel@Steinba.ch
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pubmed:publicationType |
Journal Article
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