rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5
|
pubmed:dateCreated |
2007-9-5
|
pubmed:abstractText |
The adoptive transfer of ex vivo-induced tumor-specific T-cell lines provides a promising approach for cancer immunotherapy. We have demonstrated previously the feasibility of inducing in vitro long-term anti-tumor cytotoxic T-cell (CTL) lines directed against different types of solid tumors derived from both autologous and allogeneic PBMC. We have now investigated the possibility of producing large amounts of autologous anti-tumor CTL, in compliance with good manufacturing practices, for in vivo use.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1465-3249
|
pubmed:author |
pubmed-author:CarrettoEE,
pubmed-author:La GrotteriaM CarmelaMC,
pubmed-author:LocatelliFF,
pubmed-author:MaccarioRR,
pubmed-author:MontagnaDD,
pubmed-author:MontiniEE,
pubmed-author:PedrazzoliPP,
pubmed-author:PerottiCC,
pubmed-author:SchiavoRR,
pubmed-author:SienaSS,
pubmed-author:TullinBB,
pubmed-author:TurimJJ
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pubmed:issnType |
Print
|
pubmed:volume |
9
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
499-507
|
pubmed:dateRevised |
2008-4-24
|
pubmed:meshHeading |
pubmed-meshheading:17786611-Adult,
pubmed-meshheading:17786611-Antigens, CD8,
pubmed-meshheading:17786611-Carcinoma,
pubmed-meshheading:17786611-Cell Culture Techniques,
pubmed-meshheading:17786611-Cell Line,
pubmed-meshheading:17786611-Cell Proliferation,
pubmed-meshheading:17786611-Cytotoxicity Tests, Immunologic,
pubmed-meshheading:17786611-HLA Antigens,
pubmed-meshheading:17786611-Humans,
pubmed-meshheading:17786611-Immunophenotyping,
pubmed-meshheading:17786611-Immunotherapy, Adoptive,
pubmed-meshheading:17786611-Neoplasms,
pubmed-meshheading:17786611-Sarcoma,
pubmed-meshheading:17786611-T-Lymphocyte Subsets,
pubmed-meshheading:17786611-T-Lymphocytes, Cytotoxic,
pubmed-meshheading:17786611-Treatment Outcome
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pubmed:year |
2007
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pubmed:articleTitle |
GMP production of anti-tumor cytotoxic T-cell lines for adoptive T-cell therapy in patients with solid neoplasia.
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pubmed:affiliation |
Immunology Laboratory and Pediatric Hematology/Oncology, IRCCS Policlinico San Matteo, Milan, Italy.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
|