Source:http://linkedlifedata.com/resource/pubmed/id/17786139
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
2007-9-5
|
| pubmed:abstractText |
The recurrent microlithiasis represents one of the most frequent clinical forms of lithiasis of the bile ducts. This affection is characterized by the presence of cholesterolic microgallstones on hepatic canaliculars, and belongs to a heterogeneous group of autosomal recessive liver disorders. Radiological diagnosis can be confirmed by analysis of MDR3 gene, coding a protein involved in physiologic translocation of phospholipids in bile. Discovery of MDR3 mutations is of particular interest, since normally associated with good effectiveness of medication by ursodesoxycholic acid.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
1665-2681
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
6
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
143-9
|
| pubmed:meshHeading |
pubmed-meshheading:17786139-ATP-Binding Cassette Transporters,
pubmed-meshheading:17786139-Cholecystolithiasis,
pubmed-meshheading:17786139-Choledocholithiasis,
pubmed-meshheading:17786139-Cholesterol,
pubmed-meshheading:17786139-Gallbladder,
pubmed-meshheading:17786139-Humans,
pubmed-meshheading:17786139-Liver,
pubmed-meshheading:17786139-Mutation,
pubmed-meshheading:17786139-P-Glycoproteins
|
| pubmed:articleTitle |
MDR3 mutations associated with intrahepatic and gallbladder cholesterol cholelithiasis: an update.
|
| pubmed:affiliation |
BEGIN Military Hospital, Department of Biochemistry, Saint-Mandé, France.
|
| pubmed:publicationType |
Journal Article,
Review
|