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Predicate | Object |
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rdf:type | |
lifeskim:mentions |
umls-concept:C0008051,
umls-concept:C0015780,
umls-concept:C0024554,
umls-concept:C0032105,
umls-concept:C0032659,
umls-concept:C0040132,
umls-concept:C0040135,
umls-concept:C0242693,
umls-concept:C0441889,
umls-concept:C1280500,
umls-concept:C1304649,
umls-concept:C1442792,
umls-concept:C1515926,
umls-concept:C1623788
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pubmed:issue |
6
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pubmed:dateCreated |
1992-3-6
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pubmed:abstractText |
Propylthiouracil (PTU), thyroxine (T4) or thyreoliberin (TRH) were injected in ovo to modify the thyroid state of chicken embryos. Significant sexual differences were observed in the effects of these treatments on the plasma concentrations of thyroid hormones and on plantaris muscle characteristics (DNA, RNA, populations of muscle fibers) in 3- and 35-day old male and female chickens. The T4 plasma concentration is lower in control males; it is decreased in PTU treated females and in the T4 treated females at 35 days. The T3 plasma concentration is lowered at 3 days in all treated chickens and also at 35 days in the TRH treated animals. The slow (STnO) and the fast (FTOG) fibers of the plantaris are always more numerous in males. In controls, the number of FTOG fibers remains steady between 3 and 35 days; at the same time, the number of STnO fibers rises in males only. Both PTU and T4 treatments increase the number of the FTOG and the STnO fibers respectively before and after the 3rd day. TRH treatment increases the number of STnO fibers at 3 and 35 days in males, but reduces it at 3 days in females. Thus changes in the number of FTOG fibers can be induced during in ovo myogenesis, whereas the number of STnO fibers may increase after hatching.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Propylthiouracil,
http://linkedlifedata.com/resource/pubmed/chemical/Thyroid Hormones,
http://linkedlifedata.com/resource/pubmed/chemical/Thyrotropin-Releasing Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Thyroxine,
http://linkedlifedata.com/resource/pubmed/chemical/Triiodothyronine
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pubmed:status |
MEDLINE
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pubmed:issn |
0926-5287
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
703-16
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1777062-Animals,
pubmed-meshheading:1777062-Chick Embryo,
pubmed-meshheading:1777062-Chickens,
pubmed-meshheading:1777062-Female,
pubmed-meshheading:1777062-Male,
pubmed-meshheading:1777062-Muscles,
pubmed-meshheading:1777062-Organ Size,
pubmed-meshheading:1777062-Propylthiouracil,
pubmed-meshheading:1777062-Sex Characteristics,
pubmed-meshheading:1777062-Thyroid Gland,
pubmed-meshheading:1777062-Thyroid Hormones,
pubmed-meshheading:1777062-Thyrotropin-Releasing Hormone,
pubmed-meshheading:1777062-Thyroxine,
pubmed-meshheading:1777062-Triiodothyronine
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pubmed:year |
1991
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pubmed:articleTitle |
Effects of thyroid state alterations in ovo on the plasma levels of thyroid hormones and on the populations of fibers in the plantaris muscle of male and female chickens.
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pubmed:affiliation |
INRA and USTL, Laboratoire de Neurobiologie, Montpellier, France.
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pubmed:publicationType |
Journal Article,
Comparative Study
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