Source:http://linkedlifedata.com/resource/pubmed/id/17768110
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
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| pubmed:dateCreated |
2007-11-20
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| pubmed:abstractText |
Our objective was to determine whether the goal of high-dose therapy should be a partial hematologic response or a complete response. We analyzed 282 consecutive stem cell transplant patients. A partial hematologic response was achieved in 108 patients (38%), and 93 (33%) achieved a complete hematologic response. Survival rates of patients with complete, partial, or no response were significantly different (p<0.001), even after eliminating bias from early death. The degree of response was affected by the intensity of chemotherapy conditioning, septal thickness, and cardiac biomarkers. Hematologic response translates to longer survival.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Oct
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| pubmed:issn |
1592-8721
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| pubmed:author | |
| pubmed:issnType |
Electronic
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| pubmed:volume |
92
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
1415-8
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| pubmed:meshHeading |
pubmed-meshheading:17768110-Amyloidosis,
pubmed-meshheading:17768110-Female,
pubmed-meshheading:17768110-Follow-Up Studies,
pubmed-meshheading:17768110-Humans,
pubmed-meshheading:17768110-Male,
pubmed-meshheading:17768110-Middle Aged,
pubmed-meshheading:17768110-Stem Cell Transplantation,
pubmed-meshheading:17768110-Survival Rate,
pubmed-meshheading:17768110-Treatment Outcome
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| pubmed:year |
2007
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| pubmed:articleTitle |
Effect of hematologic response on outcome of patients undergoing transplantation for primary amyloidosis: importance of achieving a complete response.
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| pubmed:affiliation |
Division of Hematology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. gertz.morie@mayo.edu
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| pubmed:publicationType |
Journal Article
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