Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2007-9-3
pubmed:abstractText
Age-related decreases in energy expenditure and physical activity have been associated with the loss of skeletal muscle and decline of food intake, possibly through a mechanism involving changes of growth hormone secretion and feeding behavior. Age-related declines of growth hormone secretion and food intake have been termed the somatopause and anorexia of aging, respectively. Ghrelin was isolated from human and rat stomachs as an endogenous ligand of growth hormone secretagogue receptor. Ghrelin stimulates growth hormone release and food intake when peripherally administered to humans. Plasma ghrelin concentration is decreased with age. Therefore, age-related decline of ghrelin secretion may cause the somatopause and anorexia of aging. Ghrelin replacement may suppress these aging processes.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0917-5857
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1392-9
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
[Hormone replacement Up-to-date. Ghrelin, growth hormone and somatopause].
pubmed:affiliation
University of Miyazaki, Faculty of Medicine, Department of Internal Medicine, Endocrinology and Metabolism, Respirology, Division of Neurology, Japan.
pubmed:publicationType
Journal Article, English Abstract, Review