Linked Life Data

17767023

Source:http://linkedlifedata.com/resource/pubmed/id/17767023

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2007-9-3
pubmed:abstractText
Estrogen has its receptor in the brain and affects the nervous system in various ways. To date, it has been paid attention whether the cognitive function and the risk of depression change due to estrogen deficiency and also whether these changes respond to hormone replacement therapy (HRT). The increase in female life expectancy accelerates the prevalence of dementia like Alzheimer Disease, so the efficacy of HRT in the cognitive function got the public attention. On the contrary, a series of large-scale randomized controlled trials (Women's Health Initiative Memory Study: WHIMS) in aged 65 years or older women showed HRT increases the risk of dementia. However, certain studies indicate HRT may have beneficial effect on dementia when being started earlier. Therefore direct application of the result of WHIMS for the climacteric women is still controversial.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0917-5857
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1349-54
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
[Hormone replacement Up-to-date. Hormone replacement therapy and brain function].
pubmed:affiliation
Osaka University Graduate School of Medicine, Department of Psychiatry, Japan.
pubmed:publicationType
Journal Article, English Abstract, Review