17764544

Source:http://linkedlifedata.com/resource/pubmed/id/17764544

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0015295, umls-concept:C0026882, umls-concept:C0079419, umls-concept:C0441633, umls-concept:C0599882, umls-concept:C1719039
pubmed:dateCreated	2007-10-16
pubmed:abstractText	p53 is commonly inactivated by mutations in the DNA-binding domain in a wide range of cancers. As mutant p53 often influences response to therapy, effective and rapid methods to scan for mutations in TP53 are likely to be of clinical value. We therefore evaluated the use of high resolution melting (HRM) as a rapid mutation scanning tool for TP53 in tumour samples.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-10430607, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-11051239, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-11079169, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-11099028, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-11179763, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-11358831, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-11742044, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-12619115, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-12765979, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-1323840, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-1409626, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-15607980, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-15607981, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-15644779, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-15772635, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-15865939, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-15948115, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-16337994, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-1648702, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-16557268, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-16733218, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-16938658, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-17184525, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-17311302, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-1924299, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-2233717, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-2267136, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-3344216, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-7852189, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-8199593, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-8402885, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-8441387, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-9101296, http://linkedlifedata.com/resource/pubmed/commentcorrection/17764544-9157982
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/100967800
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Protein p53
pubmed:status	MEDLINE
pubmed:issn	1471-2407
pubmed:author	pubmed-author:AhmedAhmed AshourAA, pubmed-author:Australian Ovarian Cancer Study Group, pubmed-author:BowtellDavid DDD, pubmed-author:BrentonJames DJD, pubmed-author:DerwinskiBB, pubmed-author:DobrovicAlexanderA, pubmed-author:EtemadmoghadamDariushD, pubmed-author:FoxStephen BSB, pubmed-author:HylandSarah JSJ, pubmed-author:KrypuyMichaelM
pubmed:issnType	Electronic
pubmed:volume	7
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	168
pubmed:dateRevised	2009-11-18
pubmed:meshHeading	pubmed-meshheading:17764544-Cell Line, Tumor, pubmed-meshheading:17764544-DNA Mutational Analysis, pubmed-meshheading:17764544-Exons, pubmed-meshheading:17764544-Female, pubmed-meshheading:17764544-Humans, pubmed-meshheading:17764544-Mutation, pubmed-meshheading:17764544-Ovarian Neoplasms, pubmed-meshheading:17764544-Polymerase Chain Reaction, pubmed-meshheading:17764544-Tumor Suppressor Protein p53
pubmed:year	2007
pubmed:articleTitle	High resolution melting for mutation scanning of TP53 exons 5-8.
pubmed:affiliation	Molecular Pathology Research and Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, Locked Bag 1, A'Beckett St, Melbourne, Victoria 8006, Australia. michael.krypuy@petermac.org
pubmed:publicationType	Journal Article, Comparative Study, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't