|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2007-9-27
|
|
pubmed:abstractText |
Neutrophil-specific antigen (NA) expression on neutrophils was analysed in 18 Japanese children before and after allogeneic stem cell transplantation (allo-SCT) with myeloablative regimen. Donor-recipient NA-incompatibility was present in one of eight NA1/NA2 heterozygous patients and eight of 10 NA1/NA1 or NA2/NA2 homozygous patients. After allo-SCTs from NA-incompatible donors, a neutrophil recipient-to-donor conversion was confirmed in all cases. Conversion to donor NA type was complete before the absolute neutrophil count reached 0.1 x 10(9)/l. These observations indicate that flow cytometric analysis of NA antigens is a simple and useful method for monitoring neutrophil engraftment in NA-incompatible allo-SCT.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0007-1048
|
|
pubmed:author |
pubmed-author:AkahaneKoshiK,
pubmed-author:GoiKumikoK,
pubmed-author:HiraokaAsakoA,
pubmed-author:HiroseKinukoK,
pubmed-author:HonnaHirokoH,
pubmed-author:InukaiTakeshiT,
pubmed-author:KagamiKeikoK,
pubmed-author:NakazawaShinpeiS,
pubmed-author:NemotoAtsushiA,
pubmed-author:SatoHirokiH,
pubmed-author:SugitaKanjiK,
pubmed-author:TakahashiKazuyaK,
pubmed-author:TaniguchiKikuyoK,
pubmed-author:TanihiroMisaeM,
pubmed-author:TezukaToruT,
pubmed-author:UnoKanakoK
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
139
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
280-3
|
|
pubmed:meshHeading |
pubmed-meshheading:17764467-Antibodies, Monoclonal,
pubmed-meshheading:17764467-Biological Markers,
pubmed-meshheading:17764467-Child,
pubmed-meshheading:17764467-Flow Cytometry,
pubmed-meshheading:17764467-Graft Survival,
pubmed-meshheading:17764467-Humans,
pubmed-meshheading:17764467-Isoantigens,
pubmed-meshheading:17764467-Neutrophils,
pubmed-meshheading:17764467-Stem Cell Transplantation,
pubmed-meshheading:17764467-Time,
pubmed-meshheading:17764467-Transplantation, Homologous
|
|
pubmed:year |
2007
|
|
pubmed:articleTitle |
Monitoring neutrophil engraftment in allogeneic stem cell transplantation by flow cytometric analysis of neutrophil-specific antigens NA1 and NA2.
|
|
pubmed:affiliation |
Department of Paediatrics, School of Medicine, University of Yamanashi, Yamanashi, Japan. tinukai@yamanashi.ac.jp
|
|
pubmed:publicationType |
Journal Article
|
