Linked Life Data

17764380

Source:http://linkedlifedata.com/resource/pubmed/id/17764380

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2007-9-3
pubmed:abstractText
Unipolar and bipolar disorders are major causes of disease burden for women in the United States. For some women, the menopausal transition can represent a time of increased vulnerability to depression, a greater risk of recurrence or instability of bipolar disorder, and an overall poorer quality of life (QOL). The physical and psychological changes of menopause and symptoms of depression may overlap, but QOL is affected doubly for women experiencing menopause-related complaints concomitantly with a unipolar or bipolar disorder. Treatments for the symptoms of menopause and for unipolar or bipolar disorder need to be chosen with careful consideration for the different stages of the menopausal transition, as well as safety, tolerability, and impact on QOL. Menopausal-related symptoms can be treated with hormonal therapies, antidepressants, and herbal supplements, but a critical window of opportunity may exist for these interventions. Bipolar disorder presents differently in women than in men and may require different medication. For instance, in women, lithium may be less effective for patients who have rapid cycling; adjuvant antidepressant medication may be required with valproate or carbamazepine; and lamotrigine may also be effective. Most of the medications that are standard treatment for bipolar disorder affect bone mineral density, and the risk for impaired QOL should be considered when choosing medication for women during this period. Insufficient information is available, however, to assess the best strategy to treat women with bipolar disorder and depression as they age.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1555-2101
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
68 Suppl 9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
16-21
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Effects and management of the menopausal transition in women with depression and bipolar disorder.
pubmed:affiliation
Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada. csoares@mcmaster.ca
pubmed:publicationType
Journal Article, Review