Source:http://linkedlifedata.com/resource/pubmed/id/17763777
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2007-9-3
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pubmed:abstractText |
Fetal bovine serum was treated by ozone for 1 hour and 3 hours before getting its surface-enhanced Raman spectra from 200 to 1 800 cm(-1). Treated with ozone for 1 hour, it shows a significant decrease in band intensity. Treated with ozone for 3 hours, the band intensity has a further decrease but not so obviously, which means that oxidation of ozone is short lived. Treated with ozone, the orderly conformations of main chains in protein such as alpha-helix, beta-sheet and beta-corner are damaged seriously. Aromatic side chains and C-S of Cys and Met also are damnified greatly. All this means that strong oxidation of ozone results in denaturation, conformational changes and even degradation in protein.
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pubmed:language |
chi
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1000-0593
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1140-2
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pubmed:meshHeading |
pubmed-meshheading:17763777-Animals,
pubmed-meshheading:17763777-Blood Proteins,
pubmed-meshheading:17763777-Cattle,
pubmed-meshheading:17763777-Fetal Blood,
pubmed-meshheading:17763777-Oxidation-Reduction,
pubmed-meshheading:17763777-Ozone,
pubmed-meshheading:17763777-Protein Conformation,
pubmed-meshheading:17763777-Protein Denaturation,
pubmed-meshheading:17763777-Protein Structure, Secondary,
pubmed-meshheading:17763777-Spectrum Analysis, Raman,
pubmed-meshheading:17763777-Time Factors
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pubmed:year |
2007
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pubmed:articleTitle |
[Surface-enhanced Raman spectra of oxidation damnification of fetal bovine serum by ozone].
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pubmed:affiliation |
Department of Biophysics, School of Physics, Nankai University, Tianjin 300071, China.
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pubmed:publicationType |
Journal Article,
English Abstract
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