rdf:type |
|
lifeskim:mentions |
umls-concept:C0007589,
umls-concept:C0023884,
umls-concept:C0038128,
umls-concept:C0205183,
umls-concept:C0205282,
umls-concept:C0205314,
umls-concept:C0221198,
umls-concept:C0242349,
umls-concept:C0370199,
umls-concept:C0386983,
umls-concept:C0679622,
umls-concept:C1269765,
umls-concept:C1511938
|
pubmed:issue |
5
|
pubmed:dateCreated |
2007-10-17
|
pubmed:abstractText |
Glypican-3 (GPC3) is a heparan sulfate proteoglycan which is elevated in the serum of patients with hepatocellular carcinoma (HCC), but not in healthy blood donors, or patients with benign liver disease. GPC3 immunohistochemistry (IHC) is a promising marker of HCC in surgical pathology. This study explores the value of GPC3 expression in liver fine-needle aspirates (FNAs) by immunocytochemistry (ICC), and compares its sensitivity and staining intensity with that of IHC.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0008-543X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
25
|
pubmed:volume |
111
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
316-22
|
pubmed:meshHeading |
pubmed-meshheading:17763368-Aged,
pubmed-meshheading:17763368-Aged, 80 and over,
pubmed-meshheading:17763368-Biopsy, Fine-Needle,
pubmed-meshheading:17763368-Carcinoma, Hepatocellular,
pubmed-meshheading:17763368-Cytodiagnosis,
pubmed-meshheading:17763368-Female,
pubmed-meshheading:17763368-Glypicans,
pubmed-meshheading:17763368-Humans,
pubmed-meshheading:17763368-Immunoenzyme Techniques,
pubmed-meshheading:17763368-Liver Neoplasms,
pubmed-meshheading:17763368-Male,
pubmed-meshheading:17763368-Middle Aged,
pubmed-meshheading:17763368-Pilot Projects,
pubmed-meshheading:17763368-Precancerous Conditions,
pubmed-meshheading:17763368-Sensitivity and Specificity,
pubmed-meshheading:17763368-Tumor Markers, Biological
|
pubmed:year |
2007
|
pubmed:articleTitle |
Glypican-3 immunocytochemistry in liver fine-needle aspirates : a novel stain to assist in the differentiation of benign and malignant liver lesions.
|
pubmed:affiliation |
Department of Pathology, University of Vermont, Burlington, Vermont, USA. dina.kandil@vtmednet.org
|
pubmed:publicationType |
Journal Article
|