rdf:type |
|
lifeskim:mentions |
umls-concept:C0013455,
umls-concept:C0018479,
umls-concept:C0020835,
umls-concept:C0026724,
umls-concept:C0185125,
umls-concept:C0205276,
umls-concept:C0871261,
umls-concept:C0914671,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2349975,
umls-concept:C2911692
|
pubmed:issue |
8
|
pubmed:dateCreated |
2007-8-31
|
pubmed:abstractText |
Nasal vaccination with P6 protein of nontypeable Haemophilus influenzae (NTHi) and CpG oligodeoxynucleotide (ODN) may be effective for the induction of NTHi-specific protective immunity in the middle ear and middle ear application of CpG ODN may possibly be a new treatment strategy for otitis media (OM).
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adjuvants, Immunologic,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Anti-Idiotypic,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Viral,
http://linkedlifedata.com/resource/pubmed/chemical/Bacterial Outer Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/CPG-oligonucleotide,
http://linkedlifedata.com/resource/pubmed/chemical/Haemophilus Vaccines,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin A,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin G,
http://linkedlifedata.com/resource/pubmed/chemical/Oligodeoxyribonucleotides,
http://linkedlifedata.com/resource/pubmed/chemical/P6 outer membrane protein...
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0001-6489
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
127
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
809-15
|
pubmed:meshHeading |
pubmed-meshheading:17762989-Adjuvants, Immunologic,
pubmed-meshheading:17762989-Administration, Topical,
pubmed-meshheading:17762989-Animals,
pubmed-meshheading:17762989-Antibodies, Anti-Idiotypic,
pubmed-meshheading:17762989-Antibodies, Viral,
pubmed-meshheading:17762989-Bacterial Outer Membrane Proteins,
pubmed-meshheading:17762989-Disease Models, Animal,
pubmed-meshheading:17762989-Ear, Middle,
pubmed-meshheading:17762989-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:17762989-Haemophilus Vaccines,
pubmed-meshheading:17762989-Haemophilus influenzae,
pubmed-meshheading:17762989-Immunity, Cellular,
pubmed-meshheading:17762989-Immunoglobulin A,
pubmed-meshheading:17762989-Immunoglobulin G,
pubmed-meshheading:17762989-Mice,
pubmed-meshheading:17762989-Mice, Inbred BALB C,
pubmed-meshheading:17762989-Mucous Membrane,
pubmed-meshheading:17762989-Oligodeoxyribonucleotides,
pubmed-meshheading:17762989-Otitis Media,
pubmed-meshheading:17762989-Treatment Outcome,
pubmed-meshheading:17762989-Vaccination
|
pubmed:year |
2007
|
pubmed:articleTitle |
Local application of CpG oligodeoxynucleotide enhances nontypeable Haemophilus influenzae-specific mucosal IgA responses in the middle ear.
|
pubmed:affiliation |
Department of Otolaryngology, Oita University Faculty of Medicine, Oita, Japan.
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pubmed:publicationType |
Journal Article
|