17761942

Source:http://linkedlifedata.com/resource/pubmed/id/17761942

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0008377, umls-concept:C0011704, umls-concept:C0017337, umls-concept:C0025914, umls-concept:C0026809, umls-concept:C0205054, umls-concept:C0442821, umls-concept:C1879547, umls-concept:C2603343
pubmed:issue	10
pubmed:dateCreated	2007-9-20
pubmed:abstractText	Characterization of cholesterol homeostasis in male mice with a genetic inactivation of 3beta-hydroxysteroid-delta24-reductase, causing replacement of almost all cholesterol with desmosterol.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9505803
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/24,25-epoxycholesterol, http://linkedlifedata.com/resource/pubmed/chemical/ABCG5 protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/ATP-Binding Cassette Transporters, http://linkedlifedata.com/resource/pubmed/chemical/Bile Acids and Salts, http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol 7-alpha-Hydroxylase, http://linkedlifedata.com/resource/pubmed/chemical/Cyp27a1 protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP27A1, http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Desmosterol, http://linkedlifedata.com/resource/pubmed/chemical/Dhcr24 protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Hydroxymethylglutaryl CoA Reductases, http://linkedlifedata.com/resource/pubmed/chemical/Lipids, http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, http://linkedlifedata.com/resource/pubmed/chemical/Nerve Tissue Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Orphan Nuclear Receptors, http://linkedlifedata.com/resource/pubmed/chemical/Oxidoreductases Acting on CH-CH..., http://linkedlifedata.com/resource/pubmed/chemical/Phytosterols, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cytoplasmic and Nuclear, http://linkedlifedata.com/resource/pubmed/chemical/cytochrome P450 7A1, mouse, http://linkedlifedata.com/resource/pubmed/chemical/liver X receptor
pubmed:status	MEDLINE
pubmed:month	Oct
pubmed:issn	1524-4636
pubmed:author	pubmed-author:BjörkhemIngemarI, pubmed-author:BrafmanAnatA, pubmed-author:DiczfalusyUlfU, pubmed-author:FeinsteinElenaE, pubmed-author:HeverinMauraM, pubmed-author:Lövgren-SandblomAnitaA, pubmed-author:LarssonLilianL, pubmed-author:MeaneySteveS, pubmed-author:OlinMariaM, pubmed-author:PariniPaoloP, pubmed-author:ShafaatiMarjanM, pubmed-author:ShafirMillicentM, pubmed-author:von BahrSaraS
pubmed:issnType	Electronic
pubmed:volume	27
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	2191-7
pubmed:dateRevised	2009-11-19
pubmed:meshHeading	pubmed-meshheading:17761942-ATP-Binding Cassette Transporters, pubmed-meshheading:17761942-Animals, pubmed-meshheading:17761942-Bile, pubmed-meshheading:17761942-Bile Acids and Salts, pubmed-meshheading:17761942-Cholesterol, pubmed-meshheading:17761942-Cholesterol 7-alpha-Hydroxylase, pubmed-meshheading:17761942-Cytochrome P-450 CYP27A1, pubmed-meshheading:17761942-DNA-Binding Proteins, pubmed-meshheading:17761942-Desmosterol, pubmed-meshheading:17761942-Feces, pubmed-meshheading:17761942-Gene Expression Regulation, pubmed-meshheading:17761942-Homeostasis, pubmed-meshheading:17761942-Hydroxymethylglutaryl CoA Reductases, pubmed-meshheading:17761942-Lipid Metabolism, pubmed-meshheading:17761942-Lipids, pubmed-meshheading:17761942-Lipoproteins, pubmed-meshheading:17761942-Liver, pubmed-meshheading:17761942-Male, pubmed-meshheading:17761942-Mice, pubmed-meshheading:17761942-Mice, Knockout, pubmed-meshheading:17761942-Nerve Tissue Proteins, pubmed-meshheading:17761942-Orphan Nuclear Receptors, pubmed-meshheading:17761942-Oxidoreductases Acting on CH-CH Group Donors, pubmed-meshheading:17761942-Phytosterols, pubmed-meshheading:17761942-RNA, Messenger, pubmed-meshheading:17761942-Receptors, Cytoplasmic and Nuclear, pubmed-meshheading:17761942-Substrate Specificity, pubmed-meshheading:17761942-Time Factors
pubmed:year	2007
pubmed:articleTitle	Studies on the cholesterol-free mouse: strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol.
pubmed:affiliation	Division of Clinical Chemistry, Karolinska University Hospital, Huddinge, S-14186, Sweden.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't