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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2007-8-31
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pubmed:databankReference |
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pubmed:abstractText |
Idiopathic hypogonadotropic hypogonadism, which may be associated with anosmia (the Kallmann syndrome) or with a normal sense of smell, is a treatable form of male infertility caused by a congenital defect in the secretion or action of gonadotropin-releasing hormone (GnRH). Patients have absent or incomplete sexual maturation by the age of 18. Idiopathic hypogonadotropic hypogonadism was previously thought to require lifelong therapy. We describe 15 men in whom reversal of idiopathic hypogonadotropic hypogonadism was sustained after discontinuation of hormonal therapy.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Extracellular Matrix Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/FGFR1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/GNRHR protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Gonadotropin-Releasing Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Gonadotropins,
http://linkedlifedata.com/resource/pubmed/chemical/KAL1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/KISS1R protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Nerve Tissue Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Fibroblast Growth...,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, G-Protein-Coupled,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, LHRH,
http://linkedlifedata.com/resource/pubmed/chemical/Testosterone
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1533-4406
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pubmed:author |
pubmed-author:BoepplePaulP,
pubmed-author:ColeLindsay WLW,
pubmed-author:CrowleyWilliam FWFJr,
pubmed-author:DwyerAndrewA,
pubmed-author:FalardeauJohnJ,
pubmed-author:GunnI GIG,
pubmed-author:HayesFrances JFJ,
pubmed-author:HughesVirginia AVA,
pubmed-author:PearceSimon HSH,
pubmed-author:PitteloudNellyN,
pubmed-author:QuintonRichardR,
pubmed-author:RaivioTaneliT
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pubmed:copyrightInfo |
Copyright 2007 Massachusetts Medical Society.
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pubmed:issnType |
Electronic
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pubmed:day |
30
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pubmed:volume |
357
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
863-73
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pubmed:dateRevised |
2010-5-26
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pubmed:meshHeading |
pubmed-meshheading:17761590-Adolescent,
pubmed-meshheading:17761590-Adult,
pubmed-meshheading:17761590-Extracellular Matrix Proteins,
pubmed-meshheading:17761590-Follow-Up Studies,
pubmed-meshheading:17761590-Gonadotropin-Releasing Hormone,
pubmed-meshheading:17761590-Gonadotropins,
pubmed-meshheading:17761590-Humans,
pubmed-meshheading:17761590-Hypogonadism,
pubmed-meshheading:17761590-Kallmann Syndrome,
pubmed-meshheading:17761590-Male,
pubmed-meshheading:17761590-Mutation,
pubmed-meshheading:17761590-Nerve Tissue Proteins,
pubmed-meshheading:17761590-Pedigree,
pubmed-meshheading:17761590-Prospective Studies,
pubmed-meshheading:17761590-Puberty, Delayed,
pubmed-meshheading:17761590-Receptor, Fibroblast Growth Factor, Type 1,
pubmed-meshheading:17761590-Receptors, G-Protein-Coupled,
pubmed-meshheading:17761590-Receptors, LHRH,
pubmed-meshheading:17761590-Remission, Spontaneous,
pubmed-meshheading:17761590-Testosterone
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pubmed:year |
2007
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pubmed:articleTitle |
Reversal of idiopathic hypogonadotropic hypogonadism.
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pubmed:affiliation |
Harvard Center for Reproductive Endocrine Sciences and the Reproductive Endocrine Unit of the Department of Medicine, Massachusetts General Hospital, Boston 02114, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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