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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2007-11-12
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pubmed:abstractText |
The recent development of new high-throughput technologies for SNP genotyping has opened the possibility of taking a genome-wide linkage approach to the search for new candidate genes involved in heredity diseases. The two major breast cancer susceptibility genes BRCA1 and BRCA2 are involved in 30% of hereditary breast cancer cases, but the discovery of additional breast cancer predisposition genes for the non-BRCA1/2 breast cancer families has so far been unsuccessful.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-11313746,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-11731797,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-11792833,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-12053178,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-12083399,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-12955716,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-12960966,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-14560309,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-15154113,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-15311375,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-15492927,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-15493062,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-15514889,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-15782173,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-15812173,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-15829238,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-15947021,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-16093727,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-16252236,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-16342186,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-16451625,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-16551709,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-16575876,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-17171685,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-17529967,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-1990835,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-8460634,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-9090499,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-9207777,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-9246012,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-9345087,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-9382090,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17760956-9634505
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2164
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pubmed:author |
pubmed-author:BenitezJavierJ,
pubmed-author:DevileePeterP,
pubmed-author:GoldgarDavidD,
pubmed-author:Gonzalez-NeiraAnnaA,
pubmed-author:GonzalezEmilioE,
pubmed-author:HoogerbruggeNicolineN,
pubmed-author:LynchHenryH,
pubmed-author:OldenburgRogier ARA,
pubmed-author:OsorioAnaA,
pubmed-author:PitaGuillermoG,
pubmed-author:Rosa-RosaJuan ManuelJM,
pubmed-author:SinilnikovaOlgaO,
pubmed-author:SoutheyMelissaM,
pubmed-author:van AsperenChristi JCJ
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pubmed:issnType |
Electronic
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
299
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:17760956-Chromosome Mapping,
pubmed-meshheading:17760956-Genes, BRCA1,
pubmed-meshheading:17760956-Genes, BRCA2,
pubmed-meshheading:17760956-Genetic Linkage,
pubmed-meshheading:17760956-Genetic Predisposition to Disease,
pubmed-meshheading:17760956-Genome, Human,
pubmed-meshheading:17760956-Humans,
pubmed-meshheading:17760956-Microsatellite Repeats,
pubmed-meshheading:17760956-Polymorphism, Single Nucleotide
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pubmed:year |
2007
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pubmed:articleTitle |
Genomewide high-density SNP linkage analysis of non-BRCA1/2 breast cancer families identifies various candidate regions and has greater power than microsatellite studies.
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pubmed:affiliation |
Genotyping Unit, CeGen, Human Cancer Genetics Programme, Spanish National Cancer Centre, Spain. agonzalez@cnio.es
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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