| pubmed-article:17760351 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17760351 | lifeskim:mentions | umls-concept:C0025663 | lld:lifeskim |
| pubmed-article:17760351 | lifeskim:mentions | umls-concept:C0597979 | lld:lifeskim |
| pubmed-article:17760351 | lifeskim:mentions | umls-concept:C0444318 | lld:lifeskim |
| pubmed-article:17760351 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
| pubmed-article:17760351 | lifeskim:mentions | umls-concept:C1527148 | lld:lifeskim |
| pubmed-article:17760351 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:17760351 | pubmed:dateCreated | 2007-8-31 | lld:pubmed |
| pubmed-article:17760351 | pubmed:abstractText | With the rapid growth of the dairy industry and the establishment of strict antimicrobial residue limits in the People's Republic of China's (PRC) milk supply, a beta-lactamase product known as "antimicrobial destroyer" was introduced into dairy production without regulatory review. We developed a method for detecting this product in milk samples based on a modified cylinder plate method. The presence of beta-lactamase is defined as a difference between the inhibitory zones of the test samples (supplemented with 25 microg/mL sulbactam plus 0.5 microg/mL penicillin G) and control samples (supplemented only with 0.5 microg/mL penicillin G) > or = 3 mm. Using this method, 77 individually packaged milk samples were randomly collected from 5 retail stores in 3 cities over a 4-month period (May to August 2006). Of the 77 samples, 49 were found to be beta-lactamase-positive. In 2 undiluted milk samples showing extremely high beta-lactamase activity, 25 microg/mL sulbactam could not inhibit penicillin G activity. Because there is a lack of safety data on beta-lactamases in milk products, these data indicated a potentially serious safety concern for the dairy industry in the PRC. | lld:pubmed |
| pubmed-article:17760351 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17760351 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17760351 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17760351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17760351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17760351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17760351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17760351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17760351 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17760351 | pubmed:issn | 1060-3271 | lld:pubmed |
| pubmed-article:17760351 | pubmed:author | pubmed-author:MaYueY | lld:pubmed |
| pubmed-article:17760351 | pubmed:author | pubmed-author:LiJingyunJ | lld:pubmed |
| pubmed-article:17760351 | pubmed:author | pubmed-author:HuChangqinC | lld:pubmed |
| pubmed-article:17760351 | pubmed:author | pubmed-author:JinShaohongS | lld:pubmed |
| pubmed-article:17760351 | pubmed:author | pubmed-author:CuiShenghuiS | lld:pubmed |
| pubmed-article:17760351 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17760351 | pubmed:volume | 90 | lld:pubmed |
| pubmed-article:17760351 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17760351 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17760351 | pubmed:pagination | 1128-32 | lld:pubmed |
| pubmed-article:17760351 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:17760351 | pubmed:meshHeading | pubmed-meshheading:17760351... | lld:pubmed |
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| pubmed-article:17760351 | pubmed:meshHeading | pubmed-meshheading:17760351... | lld:pubmed |
| pubmed-article:17760351 | pubmed:articleTitle | Development of a method for the detection of beta-lactamases in milk samples. | lld:pubmed |
| pubmed-article:17760351 | pubmed:affiliation | National Institute for the Control of Pharmaceutical and Biological Products, Department of Antibiotics, Beijing 100050, People's Republic of China. | lld:pubmed |
| pubmed-article:17760351 | pubmed:publicationType | Journal Article | lld:pubmed |
