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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1976-7-6
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pubmed:abstractText |
Right ventricular kitten papillary muscles were incubated with dibutyryl adenosine 3',5'-monophosphate (dbcAMP) at varying concentrations as low as 1 X 10(-4)M. A positive inotropic effect was observed with all concentrations of dbcAMP. Concomitant administration of 5 X 10(-4)M monobutyryl guanosine 3',5'-monophosphate (mbcGMP) and 1-2 X 10(-4)M dbcAMP prevented the inotropic response observed when dbcAMP was used alone. When higher doses of dbcAMP were used (5 X 10(-4) M, 10 X 10(-4) M), there was no significant difference in the inotropic response seen between control tissues and papillary muscles pretreated with mbcGMP.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0014-2999
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
247-51
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:177300-Animals,
pubmed-meshheading:177300-Bucladesine,
pubmed-meshheading:177300-Cats,
pubmed-meshheading:177300-Cyclic GMP,
pubmed-meshheading:177300-Dose-Response Relationship, Drug,
pubmed-meshheading:177300-Drug Interactions,
pubmed-meshheading:177300-Myocardial Contraction,
pubmed-meshheading:177300-Papillary Muscles,
pubmed-meshheading:177300-Stimulation, Chemical
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pubmed:year |
1976
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pubmed:articleTitle |
Effects of derivatives of cyclic amp and cyclic gmp on contraction force of cat papillary muscles.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.
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