Source:http://linkedlifedata.com/resource/pubmed/id/17728367
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9
|
| pubmed:dateCreated |
2007-8-30
|
| pubmed:abstractText |
Systemic Lupus International Collaborating Clinics (SLICC) comprises 27 centres from 11 countries. An inception cohort of 918 SLE patients has been assembled according to a standardized protocol between 2000 and 2006. Clinical features, classic coronary artery disease (CAD) risk factors, as well as other potential risk factors were collected. Of the 918 patients 89% were females, and of multi racial origin. Less than half the patients were living in a permanent relationship, 58% had post secondary education and 51% were employed. Eight percent had family history of SLE. At enrolment, with at mean age of diagnosis of 34.5 years, a significant number of patients already had CAD risk factors, such as hypertension (33%) and hypercholesterolemia (36%). Only 15% of the patients were postmenopausal, 16% were current smokers and 3.6% had diabetes at entry to the SLICC-RAS (Registry for Atherosclerosis). A number of patients in this multi-racial, multi-ethnic inception cohort of lupus patients have classic CAD risk factors within a mean of 5.4 months from diagnosis. This cohort will be increased to 1500 patients to be followed yearly for 10 years. This will provide a unique opportunity to evaluate risk factors for accelerated atherosclerosis in SLE.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0961-2033
|
| pubmed:author |
pubmed-author:AlarconGG,
pubmed-author:AranowCC,
pubmed-author:BanZZ,
pubmed-author:BernatskySS,
pubmed-author:BruceII,
pubmed-author:BuyonJJ,
pubmed-author:ClarkeAA,
pubmed-author:DooleyM AMA,
pubmed-author:FontJJ,
pubmed-author:FortinPP,
pubmed-author:GinzlerEE,
pubmed-author:GladmanDD,
pubmed-author:GordonCC,
pubmed-author:HanlyJJ,
pubmed-author:IbañezDD,
pubmed-author:IsenbergDD,
pubmed-author:KalunianKK,
pubmed-author:KhamashtaMM,
pubmed-author:MaddisonPP,
pubmed-author:ManziSS,
pubmed-author:MerrillJJ,
pubmed-author:NivedOO,
pubmed-author:PetriMM,
pubmed-author:Ramsey-GoldmanRR,
pubmed-author:Sanchez-GuerreroJJ,
pubmed-author:SteinssonKK,
pubmed-author:StolpHH,
pubmed-author:SturfeltGG,
pubmed-author:UrowitzM BMB,
pubmed-author:WallaceDD,
pubmed-author:ZomaAA,
pubmed-author:van VollenhovenRR
|
| pubmed:issnType |
Print
|
| pubmed:volume |
16
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
731-5
|
| pubmed:meshHeading |
pubmed-meshheading:17728367-Cohort Studies,
pubmed-meshheading:17728367-Coronary Artery Disease,
pubmed-meshheading:17728367-Diabetes Complications,
pubmed-meshheading:17728367-Female,
pubmed-meshheading:17728367-Humans,
pubmed-meshheading:17728367-Hypercholesterolemia,
pubmed-meshheading:17728367-Hypertension,
pubmed-meshheading:17728367-Lupus Erythematosus, Systemic,
pubmed-meshheading:17728367-Male,
pubmed-meshheading:17728367-Postmenopause,
pubmed-meshheading:17728367-Risk Factors,
pubmed-meshheading:17728367-Smoking,
pubmed-meshheading:17728367-Time Factors
|
| pubmed:year |
2007
|
| pubmed:articleTitle |
Clinical manifestations and coronary artery disease risk factors at diagnosis of systemic lupus erythematosus: data from an international inception cohort.
|
| pubmed:affiliation |
SLICC Registry for Atherosclerosis Coordinating Centre, University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, 399 Bathurst Street, Toronto, Ontario, Canada.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
|