Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1992-2-28
pubmed:abstractText
Two hundred and ninety-nine patients received 325 Carpentier-Edwards biological valves from April 1976 to April 1982. Valves were placed in the following positions: 150 aortic (AVR), 120 mitral (MVR), 26 multiple (MR), 2 pulmonary (PR) and 1 tricuspid (TR). The mean age was 54.7 years. The total follow-up time was 2545 patient-years. Patients were divided into different age groups: less than 40, 40-49, 50-59, 60-69 and greater than 70 years and were followed-up for reoperations and tissue failure. Ninety-three operations were performed in 91 patients (30.5%) for valve related dysfunctions. The main cause of reoperation was primary tissue failure (85%). The respective incidence and risk of reoperation in the different age groups were 51.5% and 5%, 41.5% and 4%, 32% and 3%, 18% and 2.5%, and 0% for greater than 70 years of age. The risk of reoperation decreased significantly with increasing age (P less than 0.05). The respective incidence and risk of tissue failure in the age groups were 43.8% and 4.1%, 35% and 4%, 27.3% and 3.2%, and 17.2%, 2.4% and 0%. The freedom from reoperation and tissue failure was significantly higher in the older patient (greater than 60 years) compared to the younger patients (less than 60 years). The commonest cause of failure in young patients was calcification, while in older patients it was cusp rupture. Comparing aortic and mitral bioprostheses in the different age groups showed no difference between these valves in patients less than 50 years of age.(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1010-7940
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
635-40
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed-meshheading:1772679-Adolescent, pubmed-meshheading:1772679-Adult, pubmed-meshheading:1772679-Age Factors, pubmed-meshheading:1772679-Aged, pubmed-meshheading:1772679-Bioprosthesis, pubmed-meshheading:1772679-Cause of Death, pubmed-meshheading:1772679-Child, pubmed-meshheading:1772679-Child, Preschool, pubmed-meshheading:1772679-Female, pubmed-meshheading:1772679-Follow-Up Studies, pubmed-meshheading:1772679-Heart Valve Diseases, pubmed-meshheading:1772679-Heart Valve Prosthesis, pubmed-meshheading:1772679-Hospitals, University, pubmed-meshheading:1772679-Humans, pubmed-meshheading:1772679-Incidence, pubmed-meshheading:1772679-Male, pubmed-meshheading:1772679-Middle Aged, pubmed-meshheading:1772679-Postoperative Complications, pubmed-meshheading:1772679-Prosthesis Failure, pubmed-meshheading:1772679-Reoperation, pubmed-meshheading:1772679-Sweden
pubmed:year
1991
pubmed:articleTitle
The influence of age on the durability of Carpentier-Edwards biological valves. Thirteen years follow-up.
pubmed:affiliation
Department of Thoracic and Cardiovascular Surgery, Sahlgrenska Hospital, Gothenburg University, Sweden.
pubmed:publicationType
Journal Article