Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2007-8-29
pubmed:abstractText
The corticobasal degeneration syndrome has been suggested to be part of a complex of conditions (including the different subtypes of frontotemporal dementia and progressive supranuclear palsy), which reflect a spectrum of pathological substrates. This concept is supported by the frequent clinical overlap that can be observed among patients diagnosed with these conditions. We report three clinical cases, characterized by the overlap of the clinical features of corticobasal degeneration syndrome with, respectively, nonfluent progressive aphasia, progressive supranuclear palsy and semantic dementia. Current diagnostic criteria emphasize differences in clinical presentation, which probably reflect the preferential location of pathology in the early stages of disease. However, with disease progression, a considerable clinical overlap can be expected among the different syndromes. This concept should be extended not only to the cognitive and behavioural features of the frontotemporal dementia subtypes, but also to the movement disorders of corticobasal degeneration and supranuclear palsy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0953-4180
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
159-64
pubmed:meshHeading
pubmed-meshheading:17726244-Aged, 80 and over, pubmed-meshheading:17726244-Aphasia, pubmed-meshheading:17726244-Cerebrovascular Circulation, pubmed-meshheading:17726244-Dementia, pubmed-meshheading:17726244-Electroencephalography, pubmed-meshheading:17726244-Electromyography, pubmed-meshheading:17726244-Female, pubmed-meshheading:17726244-Frontal Lobe, pubmed-meshheading:17726244-Humans, pubmed-meshheading:17726244-Magnetic Resonance Imaging, pubmed-meshheading:17726244-Male, pubmed-meshheading:17726244-Middle Aged, pubmed-meshheading:17726244-Nerve Degeneration, pubmed-meshheading:17726244-Neuropsychological Tests, pubmed-meshheading:17726244-Pyramidal Tracts, pubmed-meshheading:17726244-Severity of Illness Index, pubmed-meshheading:17726244-Supranuclear Palsy, Progressive, pubmed-meshheading:17726244-Syndrome, pubmed-meshheading:17726244-Temporal Lobe
pubmed:year
2007
pubmed:articleTitle
The clinical overlap between the corticobasal degeneration syndrome and other diseases of the frontotemporal spectrum: three case reports.
pubmed:affiliation
Department of Neurology and Neurorehabilitation, San Raffaele Turro Hospital, Milan, Italy. raggi.alberto@hsr.it
pubmed:publicationType
Journal Article, Case Reports