Linked Life Data

17723272

Source:http://linkedlifedata.com/resource/pubmed/id/17723272

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2007-9-24
pubmed:abstractText
Treatment-resistant depression (TRD) is a common clinical problem, and represents a considerable challenge to treatment, however, the pathogenesis of this disease is poorly understood. Thalamus is generally believed to have a role in the pathophysiology of depression. In this study, we adopted 1.5T (1)H magnetic resonance spectroscopy ((1)H MRS) to examine possible alterations of thalamus metabolism in 20 adult TRD patients. Our results suggested there might be damage and loss of neurons, as well as membrane phospholipids associated metabolism abnormality in the TRD thalamus.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
20
pubmed:volume
425
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
49-52
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
1H magnetic resonance spectroscopy study of thalamus in treatment resistant depressive patients.
pubmed:affiliation
Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, The Key Laboratory of Diagnostic Medicine Designated by the Ministry of Education, Chongqing, 400016, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't