|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0010132,
umls-concept:C0011155,
umls-concept:C0022661,
umls-concept:C0026809,
umls-concept:C0034809,
umls-concept:C0086597,
umls-concept:C0162429,
umls-concept:C0529997,
umls-concept:C0871125,
umls-concept:C1413709,
umls-concept:C2698739
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2008-2-1
|
|
pubmed:abstractText |
Both corticotropin-releasing factor (CRF) and glucocorticoid receptors (GR) are implicated in the psychotic symptoms of psychiatric disorders. Correspondingly, it is of interest to determine their respective involvement in the sensorimotor gating deficits displayed by transgenic mice overexpressing CRF. These mice reveal lifelong elevations of CRF and corticosterone levels.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
1873-2402
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
15
|
|
pubmed:volume |
63
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
360-8
|
|
pubmed:dateRevised |
2008-4-2
|
|
pubmed:meshHeading |
pubmed-meshheading:17716630-Acoustic Stimulation,
pubmed-meshheading:17716630-Adrenalectomy,
pubmed-meshheading:17716630-Animals,
pubmed-meshheading:17716630-Benzodioxoles,
pubmed-meshheading:17716630-Depressive Disorder, Major,
pubmed-meshheading:17716630-Disease Models, Animal,
pubmed-meshheading:17716630-Gene Expression,
pubmed-meshheading:17716630-Genotype,
pubmed-meshheading:17716630-Hormone Antagonists,
pubmed-meshheading:17716630-Infusions, Parenteral,
pubmed-meshheading:17716630-Male,
pubmed-meshheading:17716630-Mice,
pubmed-meshheading:17716630-Mice, Transgenic,
pubmed-meshheading:17716630-Mifepristone,
pubmed-meshheading:17716630-Psychotic Disorders,
pubmed-meshheading:17716630-Receptors, Corticotropin-Releasing Hormone,
pubmed-meshheading:17716630-Receptors, Glucocorticoid,
pubmed-meshheading:17716630-Startle Reaction,
pubmed-meshheading:17716630-Steroids
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
CRF1 not glucocorticoid receptors mediate prepulse inhibition deficits in mice overexpressing CRF.
|
|
pubmed:affiliation |
Psychopharmacology, Department of Pharmaceutical Sciences, Rudolf Magnus Institute of Neuroscience and Utrecht Institute of Pharmaceutical Sciences, Utrecht, the Netherlands. l.groenink@uu.nl
|
|
pubmed:publicationType |
Journal Article
|
