Source:http://linkedlifedata.com/resource/pubmed/id/17716118
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2007-8-24
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pubmed:abstractText |
Magnetic nanoparticles and their magnetofluorescent analogues have become important tools for in vivo imaging using magnetic resonance imaging and fluorescent optical methods. A number of monodisperse magnetic nanoparticle preparations have been developed over the last decade for angiogenesis imaging, cancer staging, tracking of immune cells (monocyte/macrophage, T cells) and for molecular and cellular targeting. Phage display and data mining have enabled the procurement of novel tissue- or receptor-specific peptides, while high-throughput screening of diversity-oriented synthesis libraries has identified small molecules that permit or prevent uptake by specific cell types. Next-generation magnetic nanoparticles are expected to be truly multifunctional, incorporating therapeutic functionalities and further enhancing an already diverse repertoire of capabilities.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1748-6963
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
153-67
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pubmed:dateRevised |
2010-1-28
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pubmed:meshHeading | |
pubmed:year |
2007
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pubmed:articleTitle |
Targeted delivery of multifunctional magnetic nanoparticles.
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pubmed:affiliation |
Center for Molecular Imaging Research, Harvard Medical School and Massachusetts General Hospital, 149 13th St, Rm 5406, Charlestown, MA 02129, USA. jason_mccarthy@hms.harvard.edu
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pubmed:publicationType |
Journal Article,
Review,
Research Support, N.I.H., Extramural
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