Alp7/TACC has been identified as an important target for Ran GTPase in spindle formation in fission yeast. This discovery underlines a general role for Ran in orchestrating mitosis in all eukaryotes.
Biomedical Research Centre, Level 5, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, Scotland, UK. p.r.clarke@dundee.ac.uk