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pubmed-article:17714552pubmed:abstractTextChemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) has been revealed to be a novel receptor for prostaglandin (PG) D(2), which is a major mast cell product released during the allergic response. The aim of this study was to analyze the effects of a newly developed small molecule antagonist of CRTH2, Cay10471, on eosinophil function with respect to recruitment, respiratory burst and degranulation.lld:pubmed
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pubmed-article:17714552pubmed:articleTitleA novel antagonist of CRTH2 blocks eosinophil release from bone marrow, chemotaxis and respiratory burst.lld:pubmed
pubmed-article:17714552pubmed:affiliationInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Graz, Austria.lld:pubmed
pubmed-article:17714552pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17714552pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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