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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2007-8-22
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pubmed:abstractText |
Apolipoprotein A-IV (apoA-IV), an intestinally and cerebrally synthesized satiety factor and anti-atherogenic plasma apolipoprotein, was recently identified as an anti-inflammatory protein. In order to elucidate whether intestinal apoA-IV exerts similar repair function as its hepatic homologue apolipoprotein A-V (apoA-V), apoA-IV-interactive proteins were searched and in vitro functional studies were performed with apoA-IV overexpressing cells. ApoA-IV was also analyzed in the intestinal mucosa of patients with inflammatory bowel diseases (IBD), together with other genes involved in epithelial junctional integrity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0018-5043
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pubmed:author |
pubmed-author:BoettcherAA,
pubmed-author:BornsteinS RSR,
pubmed-author:BuechlerCC,
pubmed-author:DieplingerHH,
pubmed-author:KronenbergFF,
pubmed-author:LangmannTT,
pubmed-author:LiebischGG,
pubmed-author:MoehleCC,
pubmed-author:OrsóEE,
pubmed-author:RitterMM,
pubmed-author:SchmittII,
pubmed-author:StremmelWW,
pubmed-author:SzakszonKK,
pubmed-author:WernerTT
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pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
601-11
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pubmed:dateRevised |
2009-2-19
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pubmed:meshHeading |
pubmed-meshheading:17712726-Apolipoproteins A,
pubmed-meshheading:17712726-Caco-2 Cells,
pubmed-meshheading:17712726-Cell Membrane Permeability,
pubmed-meshheading:17712726-Gene Expression Profiling,
pubmed-meshheading:17712726-Green Fluorescent Proteins,
pubmed-meshheading:17712726-HT29 Cells,
pubmed-meshheading:17712726-Humans,
pubmed-meshheading:17712726-Inflammatory Bowel Diseases,
pubmed-meshheading:17712726-Intercellular Junctions,
pubmed-meshheading:17712726-Intestinal Mucosa,
pubmed-meshheading:17712726-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:17712726-Protein Binding,
pubmed-meshheading:17712726-RNA, Messenger,
pubmed-meshheading:17712726-Recombinant Fusion Proteins,
pubmed-meshheading:17712726-Satiation,
pubmed-meshheading:17712726-Transfection,
pubmed-meshheading:17712726-alpha Catenin
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pubmed:year |
2007
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pubmed:articleTitle |
The satiety factor apolipoprotein A-IV modulates intestinal epithelial permeability through its interaction with alpha-catenin: implications for inflammatory bowel diseases.
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pubmed:affiliation |
Institute for Clinical Chemistry and Laboratory Medicine, University Clinic of Regensburg, Regensburg, and Medical Clinic III, University Hospital Carl Gustav Carus, Dresden, Germany. evelyn.orso@klinik.uni-regensburg.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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