Linked Life Data

17710850

Source:http://linkedlifedata.com/resource/pubmed/id/17710850

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2007-8-22
pubmed:abstractText
Evolution of transcriptional regulation is often seen as being driven by the origin of transcription factor binding sites in cis-regulatory DNA. But there is strong evidence that transcriptional specificity of transcription factor proteins is determined by protein-protein interaction with other transcription factors. Here we summarize the evidence that transcription factor protein function itself is evolving and suggest that this might play an integral if not leading role in the evolution of gene regulation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1528-2511
pubmed:author
pubmed:issnType
Print
pubmed:volume
284
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
116-25; discussion 125-9, 158-63
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Tinkering with transcription factor proteins: the role of transcription factor adaptation in developmental evolution.
pubmed:affiliation
Department of Ecology and Evolutionary Biology, Yale University, Howard Hughes Medical Institute, New Haven, CT 06520-8106, USA.
pubmed:publicationType
Journal Article, Review