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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2007-10-15
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pubmed:abstractText |
Chronic ischemia is associated with alterations in genes that result in myocardial remodeling. An important biochemical basis of cardiac remodeling is generation of reactive oxygen species (ROS). A few studies have suggested that acute ischemia triggers signals for remodeling. We examined the hypothesis that targeted deletion of lectin-like oxidized-LDL receptor (LOX-1) may inhibit signals related to cardiac remodeling.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0008-6363
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
292-302
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pubmed:meshHeading |
pubmed-meshheading:17707356-Animals,
pubmed-meshheading:17707356-Collagen Type I,
pubmed-meshheading:17707356-Fibronectins,
pubmed-meshheading:17707356-Metalloproteases,
pubmed-meshheading:17707356-Mice,
pubmed-meshheading:17707356-Mice, Inbred C57BL,
pubmed-meshheading:17707356-Myocardial Ischemia,
pubmed-meshheading:17707356-Myocardial Reperfusion Injury,
pubmed-meshheading:17707356-Osteopontin,
pubmed-meshheading:17707356-Oxidative Stress,
pubmed-meshheading:17707356-RNA, Messenger,
pubmed-meshheading:17707356-Scavenger Receptors, Class E,
pubmed-meshheading:17707356-Signal Transduction,
pubmed-meshheading:17707356-Ventricular Remodeling
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pubmed:year |
2007
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pubmed:articleTitle |
LOX-1 deletion alters signals of myocardial remodeling immediately after ischemia-reperfusion.
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pubmed:affiliation |
Department of Internal Medicine, University of Arkansas for Medical Sciences, Central Arkansas Veterans Healthcare System, Little Rock, AR 72205-7199, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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