Linked Life Data

17704643

Source:http://linkedlifedata.com/resource/pubmed/id/17704643

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
20
pubmed:dateCreated
2007-10-24
pubmed:abstractText
Strong epidemiological studies clearly show that reduction in body fat content decreases the risk for many clinical conditions including diabetes, hypertension, coronary atherosclerotic heart disease and some forms of cancer. Therefore, detailed understanding of the mechanisms underlying how fat pads expand appears crucial. Extensive studies already identified a cohort of transcription factors involved in adipocyte differentiation but the fine interrelationship between the myriads of cellular and molecular events occurring during this complex biological process is far from being completely understood. Since the cloning of the first coregulator, the impact of those molecules has dramatically increased. In this review, we will summarize the emerging impact of coregulators on energy balance with a specific interest for fat formation. Emphasis will be given to the coactivators of the SRC (p160) family.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1551-4005
pubmed:author
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2448-52
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Coregulators in adipogenesis: what could we learn from the SRC (p160) coactivator family?
pubmed:affiliation
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
pubmed:publicationType
Journal Article, Review, Research Support, N.I.H., Extramural