| pubmed-article:17702648 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17702648 | lifeskim:mentions | umls-concept:C0015576 | lld:lifeskim |
| pubmed-article:17702648 | lifeskim:mentions | umls-concept:C0205474 | lld:lifeskim |
| pubmed-article:17702648 | lifeskim:mentions | umls-concept:C0026926 | lld:lifeskim |
| pubmed-article:17702648 | lifeskim:mentions | umls-concept:C0040648 | lld:lifeskim |
| pubmed-article:17702648 | lifeskim:mentions | umls-concept:C1413716 | lld:lifeskim |
| pubmed-article:17702648 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:17702648 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:17702648 | lifeskim:mentions | umls-concept:C0871161 | lld:lifeskim |
| pubmed-article:17702648 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:17702648 | pubmed:dateCreated | 2007-9-17 | lld:pubmed |
| pubmed-article:17702648 | pubmed:abstractText | Cyclic AMP (cAMP) receptor protein (CRP)/fumarate nitrate reductase regulator (FNR) family proteins are actively associated with defense against low oxygen stress, starvation and extreme temperature conditions. They are DNA-binding proteins and regulate target genes carrying the regulatory CRP/FNR cognate nucleotide sequence elements. Recombinant protein encoded by the Mycobacterium tuberculosis ORF Rv3676, a putative CRP/FNR regulator, was purified from Escherichia coli and was found to exist as dimer, devoid of any metal cation cofactor. Purified rRv3676 exhibited cAMP binding in a concentration-dependent manner. At lower concentrations of cAMP (6-10 microM) rRv3676 shows positive cooperativity; at 10 microM cAMP the protein exists in the most open conformation. rRv3676 could bind specifically to the putative CRP/FNR nucleotide sequence elements as evident from electrophoretic mobility shift assay. | lld:pubmed |
| pubmed-article:17702648 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17702648 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17702648 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17702648 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17702648 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17702648 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17702648 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17702648 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17702648 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17702648 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17702648 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17702648 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17702648 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:17702648 | pubmed:issn | 1438-4221 | lld:pubmed |
| pubmed-article:17702648 | pubmed:author | pubmed-author:HasnainSeyed... | lld:pubmed |
| pubmed-article:17702648 | pubmed:author | pubmed-author:TundupSmanlaS | lld:pubmed |
| pubmed-article:17702648 | pubmed:author | pubmed-author:AkhterYusufY | lld:pubmed |
| pubmed-article:17702648 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17702648 | pubmed:volume | 297 | lld:pubmed |
| pubmed-article:17702648 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17702648 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17702648 | pubmed:pagination | 451-7 | lld:pubmed |
| pubmed-article:17702648 | pubmed:meshHeading | pubmed-meshheading:17702648... | lld:pubmed |
| pubmed-article:17702648 | pubmed:meshHeading | pubmed-meshheading:17702648... | lld:pubmed |
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| pubmed-article:17702648 | pubmed:meshHeading | pubmed-meshheading:17702648... | lld:pubmed |
| pubmed-article:17702648 | pubmed:meshHeading | pubmed-meshheading:17702648... | lld:pubmed |
| pubmed-article:17702648 | pubmed:meshHeading | pubmed-meshheading:17702648... | lld:pubmed |
| pubmed-article:17702648 | pubmed:meshHeading | pubmed-meshheading:17702648... | lld:pubmed |
| pubmed-article:17702648 | pubmed:meshHeading | pubmed-meshheading:17702648... | lld:pubmed |
| pubmed-article:17702648 | pubmed:meshHeading | pubmed-meshheading:17702648... | lld:pubmed |
| pubmed-article:17702648 | pubmed:meshHeading | pubmed-meshheading:17702648... | lld:pubmed |
| pubmed-article:17702648 | pubmed:meshHeading | pubmed-meshheading:17702648... | lld:pubmed |
| pubmed-article:17702648 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17702648 | pubmed:articleTitle | Novel biochemical properties of a CRP/FNR family transcription factor from Mycobacterium tuberculosis. | lld:pubmed |
| pubmed-article:17702648 | pubmed:affiliation | Laboratory of Molecular and Cellular Biology, CDFD, Hyderabad 500076, India. | lld:pubmed |
| pubmed-article:17702648 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17702648 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:885502 | entrezgene:pubmed | pubmed-article:17702648 | lld:entrezgene |
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