Linked Life Data

17702435

Source:http://linkedlifedata.com/resource/pubmed/id/17702435

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2007-8-17
pubmed:abstractText
Despite the significant advances that have been made in the treatment of chronic hepatitis C the efficacy of treatment response seems to be unsatisfactory. Treatment failure concern above one half of treated patients. It is estimated that the number of non-responders will be systematically increased. For these reasons as treatment strategies in these patients there is a need to define optimal way to use new therapies as: extending of treatment duration, higher initial doses of administered medications, an increase of patients adherence, changing of kind of pegylated interferon or treatment combinations PEG IFN + RBV with other drugs, especially HCV-enzymes inhibitors. In the work the data of efficacy of retherapy with PEG IFN alfa-2a+RBV administered during 72 weeks were present. Retreatment with PEG IFN alpha-2a and RBV in patients who fail to achieve SVR in the treatment with PEG IFN alpha-2b+RBV revealed high early viral response, in patients with advanced liver histology too. In the future there are planned treatment of chronic hepatitis C with combined therapy with IFN, specific HCV-enzymes inhibitors and antiviral medications.
pubmed:language
pol
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0033-2100
pubmed:author
pubmed:issnType
Print
pubmed:volume
61
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
23-7
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
[PEG IFN alpha-2a in the treatment of chronic hepatitis C in patients with treatment failure].
pubmed:affiliation
Katedra i Klinika Chorób Zaka?nych i Hepatologii, Collegium Medicum Uniwersytetu Miko?aja Kopemika w Toruniu. kikchzak@cm.umk.pl
pubmed:publicationType
Journal Article, English Abstract, Review