Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2007-10-23
pubmed:abstractText
In this prospective multicentric study, we investigated the contribution of positron emission tomography (PET) scanning to the staging of Hodgkin's lymphoma (HL) by computed tomography (CT) and attempted to determine whether it has any impact on therapeutic approach. One hundred eighty six consecutive patients with HL from six Italian centers were enrolled in this study. They were staged with conventional methods; 2-[fluorine-18]fluoro-2-deoxy-D: -glucose PET scanning were prospectively compared to CT. CT and FDG-PET stages were concordant in 156 patients (84%) and discordant in 30 patients (16%). PET stage in comparison to CT stage was higher in 27 patients (14%) and lower in 3 patients (1%). The programmed treatment strategy was modified in 11 out of 30 patients (37%) after the definition of final stage. If we considered the 123 CT staged patients with localized stage, ten patients (8%) with a change of stage from localized to advanced after PET evaluation were treated with different strategy. FDG-PET was shown to be a relevant, non-invasive method that supplements conventional procedures and should therefore be used routinely to stage HL, particularly in early stage patients, where a change in stage may modify disease management.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0939-5555
pubmed:author
pubmed:issnType
Print
pubmed:volume
86
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
897-903
pubmed:meshHeading
pubmed-meshheading:17701410-Adolescent, pubmed-meshheading:17701410-Adult, pubmed-meshheading:17701410-Aged, pubmed-meshheading:17701410-Bone Marrow, pubmed-meshheading:17701410-Disease Management, pubmed-meshheading:17701410-Female, pubmed-meshheading:17701410-Fluorine Radioisotopes, pubmed-meshheading:17701410-Fluorodeoxyglucose F18, pubmed-meshheading:17701410-Hodgkin Disease, pubmed-meshheading:17701410-Humans, pubmed-meshheading:17701410-Italy, pubmed-meshheading:17701410-Male, pubmed-meshheading:17701410-Middle Aged, pubmed-meshheading:17701410-Neoplasm Staging, pubmed-meshheading:17701410-Positron-Emission Tomography, pubmed-meshheading:17701410-Predictive Value of Tests, pubmed-meshheading:17701410-Prospective Studies, pubmed-meshheading:17701410-Radiopharmaceuticals, pubmed-meshheading:17701410-Tomography, X-Ray Computed
pubmed:year
2007
pubmed:articleTitle
Positron emission tomography in the staging of patients with Hodgkin's lymphoma. A prospective multicentric study by the Intergruppo Italiano Linfomi.
pubmed:affiliation
Hematology and Nuclear Medicine, Careggi Hospital and University of Florence, Florence, Italy. l.rigacci@dac.unifi.it
pubmed:publicationType
Journal Article, Comparative Study, Controlled Clinical Trial, Multicenter Study