Lactate, like glucose, has recently been found to be an energy substrate for neural activity. It is indicated that lactate is produced by astrocytes under the regulation of glutamatergic tone.
Department of Neuropsychiatry, University of Toyama Graduate School of Medicine and Pharmaceutical Science, 2630 Sugitani, Toyama 930-0194, Japan. uehara@med.u-toyama.ac.jp