Linked Life Data

17699484

Source:http://linkedlifedata.com/resource/pubmed/id/17699484

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2007-8-16
pubmed:abstractText
Aminoglycoside antibiotic efficacy is related to peak concentration (C(max)) and postantibiotic effect, whereas toxicity is directly related to body exposure as measured by area under the serum concentration versus time curve (AUC). On the basis of pharmacokinetic simulation models, tobramycin administration during the first 30 min of high-flux hemodialysis achieves similar C(max) but significantly lower AUC and prehemodialysis concentrations compared with conventional dosing in the last 30 min of hemodialysis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1555-905X
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
694-9
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Administration of tobramycin in the beginning of the hemodialysis session: a novel intradialytic dosing regimen.
pubmed:affiliation
Faculty of Pharmacy, Pharmaceutics Department, Cairo University, Cairo, Egypt.
pubmed:publicationType
Journal Article, Comparative Study